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Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity
Acetylation is known to regulate the activity of cytosolic phosphoenolpyruvate carboxykinase (PCK1), a key enzyme in gluconeogenesis, by promoting the reverse reaction of the enzyme (converting phosphoenolpyruvate to oxaloacetate). It is also known that the histone acetyltransferase p300 can induce...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948413/ https://ncbi.nlm.nih.gov/pubmed/33334880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015103 |
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