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c.A2456C-substitution in Pck1 changes the enzyme kinetic and functional properties modifying fat distribution in pigs

Cytosolic phosphoenolpyruvate carboxykinase, PCK1, is one of the main regulatory enzymes of gluconeogenesis and glyceroneogenesis. The substitution of a single amino acid (Met139Leu) in PCK1 as a consequence of a single nucleotide polymorphism (SNP), c.A2456C, is associated in the pig to a negative...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Latorre, Pedro, Burgos, Carmen, Hidalgo, Jorge, Varona, Luis, Carrodeguas, José Alberto, López-Buesa, Pascual
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726144/
https://ncbi.nlm.nih.gov/pubmed/26792594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19617
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