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RIPK3 Is Largely Dispensable for RIG-I-Like Receptor- and Type I Interferon-Driven Transcriptional Responses to Influenza A Virus in Murine Fibroblasts

The kinase RIPK3 is a key regulator of cell death responses to a growing number of viral and microbial agents. We have found that influenza A virus (IAV)-mediated cell death is largely reliant on RIPK3 and that RIPK3-deficient mice are notably more susceptible to lethal infection by IAV than their w...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Nogusa, Shoko, Slifker, Michael J., Ingram, Justin P., Thapa, Roshan J., Balachandran, Siddharth
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938532/
https://ncbi.nlm.nih.gov/pubmed/27391363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158774
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