Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington’s Disease

Recent systems-based analyses have demonstrated that sleep and stress traits emerge from shared genetic and transcriptional networks, and clinical work has elucidated the emergence of sleep dysfunction and stress susceptibility as early symptoms of Huntington's disease. Understanding the biolog...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Scarpa, Joseph R., Jiang, Peng, Losic, Bojan, Readhead, Ben, Gao, Vance D., Dudley, Joel T., Vitaterna, Martha H., Turek, Fred W., Kasarskis, Andrew
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938493/
https://ncbi.nlm.nih.gov/pubmed/27390852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006137
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