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Parkinson’s Disease is Associated with Dysregulations of a Dopamine-Modulated Gene Network Relevant to Sleep and Affective Neurobehaviors in the Striatum

In addition to the characteristic motor symptoms, Parkinson’s disease (PD) often involves a constellation of sleep and mood symptoms. However, the mechanisms underlying these comorbidities are largely unknown. We have previously reconstructed gene networks in the striatum of a population of (C57BL/6...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jiang, Peng, Scarpa, Joseph R., Gao, Vance D., Vitaterna, Martha Hotz, Kasarskis, Andrew, Turek, Fred W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423036/
https://ncbi.nlm.nih.gov/pubmed/30886221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41248-4
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