TLR4 Deficiency Protects against Hepatic Fibrosis and Diethylnitrosamine-Induced Pre-Carcinogenic Liver Injury in Fibrotic Liver

BACKGROUND: The development of hepatocellular carcinoma (HCC) is a common consequence of advanced liver fibrosis but the interactions between fibrogenesis and carcinogenesis are still poorly understood. Recently it has been shown that HCC promotion depends on Toll-like receptor (TLR) 4. Pre-cancerog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Weber, Susanne Nicole, Bohner, Annika, Dapito, Dianne H., Schwabe, Robert F., Lammert, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938399/
https://ncbi.nlm.nih.gov/pubmed/27391331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158819
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