TLR4 Deficiency Protects against Hepatic Fibrosis and Diethylnitrosamine-Induced Pre-Carcinogenic Liver Injury in Fibrotic Liver

BACKGROUND: The development of hepatocellular carcinoma (HCC) is a common consequence of advanced liver fibrosis but the interactions between fibrogenesis and carcinogenesis are still poorly understood. Recently it has been shown that HCC promotion depends on Toll-like receptor (TLR) 4. Pre-cancerog...

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Vydáno v:PLoS One
Hlavní autoři: Weber, Susanne Nicole, Bohner, Annika, Dapito, Dianne H., Schwabe, Robert F., Lammert, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938399/
https://ncbi.nlm.nih.gov/pubmed/27391331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158819
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