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Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma

BACKGROUND & AIMS: Transforming growth factor-β (TGFB) has key functions in fibrogenic cells, promoting fibrosis development in the liver and other organs. In contrast, the functions of TGFB in liver epithelial cells are not well understood, despite their high level of responsiveness to TGFB. We...

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Publicat a:Gastroenterology
Autors principals: Mu, Xueru, Pradere, Jean-Philippe, Affò, Silvia, Dapito, Dianne H., Friedman, Richard, Lefkovitch, Jay H., Schwabe, Robert F.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490681/
https://ncbi.nlm.nih.gov/pubmed/26627606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.11.039
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