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Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma

BACKGROUND & AIMS: Transforming growth factor-β (TGFB) has key functions in fibrogenic cells, promoting fibrosis development in the liver and other organs. In contrast, the functions of TGFB in liver epithelial cells are not well understood, despite their high level of responsiveness to TGFB. We...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Mu, Xueru, Pradere, Jean-Philippe, Affò, Silvia, Dapito, Dianne H., Friedman, Richard, Lefkovitch, Jay H., Schwabe, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490681/
https://ncbi.nlm.nih.gov/pubmed/26627606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.11.039
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