Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity

Pediatric cancers, including Ewing sarcoma (ES), are only weakly immunogenic and the tumor-patients' immune system often is devoid of effector T cells for tumor elimination. Based on expression profiling technology, targetable tumor-associated antigens (TAA) are identified and exploited for eng...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncoimmunology
Päätekijät: Schirmer, David, Grünewald, Thomas G. P., Klar, Richard, Schmidt, Oxana, Wohlleber, Dirk, Rubío, Rebeca Alba, Uckert, Wolfgang, Thiel, Uwe, Bohne, Felix, Busch, Dirk H., Krackhardt, Angela M., Burdach, Stefan, Richter, Günther H. S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938321/
https://ncbi.nlm.nih.gov/pubmed/27471654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1175795
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