Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells

BACKGROUND: The development of a successful immunotherapy is hampered by an ineffective T-cell repertoire against tumour antigens and the inability of the patient's immune system to overcome tolerance-inducing mechanisms. Here, we test the specific recognition and lytical potential of allo-rest...

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Hlavní autoři: Thiel, U, Pirson, S, Müller-Spahn, C, Conrad, H, Busch, D H, Bernhard, H, Burdach, S, Richter, G H S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065285/
https://ncbi.nlm.nih.gov/pubmed/21407224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.54
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