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Folate Receptor Targeted Delivery of siRNA and Paclitaxel to Ovarian Cancer Cells via Folate Conjugated Triblock Copolymer to Overcome TLR4 Driven Chemotherapy Resistance

This paper focuses on the ability of a folate-decorated triblock copolymer to deliver a targeted dose of siRNA in order to overcome chemotherapy resistance which can commonly cause complications in ovarian cancer patients. The micelleplexes that are formed upon electrostatic interaction with siRNA a...

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Vydáno v:Biomacromolecules
Hlavní autoři: Jones, Steven K., Lizzio, Vincent, Merkel, Olivia M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937801/
https://ncbi.nlm.nih.gov/pubmed/26636884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.5b01189
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