Synthesis of a novel adamantyl nitroxide derivative with potent anti-hepatoma activity in vitro and in vivo

In this study, a novel adamantyl nitroxide derivative was synthesized and its antitumor activities in vitro and in vivo were investigated. The adamantyl nitroxide derivative 4 displayed a potent anticancer activity against all the tested human hepatoma cells, especially with IC(50) of 68.1 μM in Bel...

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Pubblicato in:Am J Cancer Res
Autori principali: Sun, Jin, Wang, Shan, Bu, Wei, Wei, Meng-Ying, Li, Wei-Wei, Yao, Min-Na, Ma, Zhong-Ying, Lu, Cheng-Tao, Li, Hui-Hui, Hu, Na-Ping, Zhang, En-Hu, Yang, Guo-Dong, Wen, Ai-Dong, Zhu, Xiao-He
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937732/
https://ncbi.nlm.nih.gov/pubmed/27429843
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