Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics

We present protease specificity profiling based on quantitative proteomics in combination with proteome-derived peptide libraries. Peptide libraries are generated by endoproteolytic digestion of proteomes without chemical modification of primary amines before exposure to a protease under investigati...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Biniossek, Martin L., Niemer, Melanie, Maksimchuk, Ken, Mayer, Bettina, Fuchs, Julian, Huesgen, Pitter F., McCafferty, Dewey G., Turk, Boris, Fritz, Guenther, Mayer, Jens, Haecker, Georg, Mach, Lukas, Schilling, Oliver
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
Subjects:
Technological Innovation and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937521/
https://ncbi.nlm.nih.gov/pubmed/27122596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O115.056671
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