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Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen()()

Clostridial collagenases are among the most efficient degraders of collagen. Most clostridia are saprophytes and secrete proteases to utilize proteins in their environment as carbon sources; during anaerobic infections, collagenases play a crucial role in host colonization. Several medical and biote...

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Detalhes bibliográficos
Main Authors: Eckhard, Ulrich, Huesgen, Pitter F., Brandstetter, Hans, Overall, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985423/
https://ncbi.nlm.nih.gov/pubmed/24125730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2013.10.004
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