A novel role for poly(C) binding proteins in programmed ribosomal frameshifting

Translational control through programmed ribosomal frameshifting (PRF) is exploited widely by viruses and increasingly documented in cellular genes. Frameshifting is induced by mRNA secondary structures that compromise ribosome fidelity during decoding of a heptanucleotide ‘slippery’ sequence. The n...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Napthine, Sawsan, Treffers, Emmely E., Bell, Susanne, Goodfellow, Ian, Fang, Ying, Firth, Andrew E., Snijder, Eric J., Brierley, Ian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
NAR Breakthrough Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937337/
https://ncbi.nlm.nih.gov/pubmed/27257056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw480
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