A novel role for poly(C) binding proteins in programmed ribosomal frameshifting

Translational control through programmed ribosomal frameshifting (PRF) is exploited widely by viruses and increasingly documented in cellular genes. Frameshifting is induced by mRNA secondary structures that compromise ribosome fidelity during decoding of a heptanucleotide ‘slippery’ sequence. The n...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Napthine, Sawsan, Treffers, Emmely E., Bell, Susanne, Goodfellow, Ian, Fang, Ying, Firth, Andrew E., Snijder, Eric J., Brierley, Ian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
NAR Breakthrough Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937337/
https://ncbi.nlm.nih.gov/pubmed/27257056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw480
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