A novel role for poly(C) binding proteins in programmed ribosomal frameshifting

Translational control through programmed ribosomal frameshifting (PRF) is exploited widely by viruses and increasingly documented in cellular genes. Frameshifting is induced by mRNA secondary structures that compromise ribosome fidelity during decoding of a heptanucleotide ‘slippery’ sequence. The n...

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Publicat a:Nucleic Acids Res
Autors principals: Napthine, Sawsan, Treffers, Emmely E., Bell, Susanne, Goodfellow, Ian, Fang, Ying, Firth, Andrew E., Snijder, Eric J., Brierley, Ian
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
NAR Breakthrough Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937337/
https://ncbi.nlm.nih.gov/pubmed/27257056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw480
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