A novel role for poly(C) binding proteins in programmed ribosomal frameshifting

Translational control through programmed ribosomal frameshifting (PRF) is exploited widely by viruses and increasingly documented in cellular genes. Frameshifting is induced by mRNA secondary structures that compromise ribosome fidelity during decoding of a heptanucleotide ‘slippery’ sequence. The n...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Napthine, Sawsan, Treffers, Emmely E., Bell, Susanne, Goodfellow, Ian, Fang, Ying, Firth, Andrew E., Snijder, Eric J., Brierley, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
NAR Breakthrough Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937337/
https://ncbi.nlm.nih.gov/pubmed/27257056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw480
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