A novel role for poly(C) binding proteins in programmed ribosomal frameshifting

Translational control through programmed ribosomal frameshifting (PRF) is exploited widely by viruses and increasingly documented in cellular genes. Frameshifting is induced by mRNA secondary structures that compromise ribosome fidelity during decoding of a heptanucleotide ‘slippery’ sequence. The n...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Napthine, Sawsan, Treffers, Emmely E., Bell, Susanne, Goodfellow, Ian, Fang, Ying, Firth, Andrew E., Snijder, Eric J., Brierley, Ian
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
NAR Breakthrough Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937337/
https://ncbi.nlm.nih.gov/pubmed/27257056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw480
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