Two sets of RNAi components are required for heterochromatin formation in trans triggered by truncated transgenes

Across kingdoms, RNA interference (RNAi) has been shown to control gene expression at the transcriptional- or the post-transcriptional level. Here, we describe a mechanism which involves both aspects: truncated transgenes, which fail to produce intact mRNA, induce siRNA accumulation and silencing of...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Götz, Ulrike, Marker, Simone, Cheaib, Miriam, Andresen, Karsten, Shrestha, Simon, Durai, Dilip A., Nordström, Karl J., Schulz, Marcel H., Simon, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937312/
https://ncbi.nlm.nih.gov/pubmed/27085807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw267
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