Two sets of RNAi components are required for heterochromatin formation in trans triggered by truncated transgenes

Across kingdoms, RNA interference (RNAi) has been shown to control gene expression at the transcriptional- or the post-transcriptional level. Here, we describe a mechanism which involves both aspects: truncated transgenes, which fail to produce intact mRNA, induce siRNA accumulation and silencing of...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Götz, Ulrike, Marker, Simone, Cheaib, Miriam, Andresen, Karsten, Shrestha, Simon, Durai, Dilip A., Nordström, Karl J., Schulz, Marcel H., Simon, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937312/
https://ncbi.nlm.nih.gov/pubmed/27085807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw267
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