Two sets of RNAi components are required for heterochromatin formation in trans triggered by truncated transgenes

Across kingdoms, RNA interference (RNAi) has been shown to control gene expression at the transcriptional- or the post-transcriptional level. Here, we describe a mechanism which involves both aspects: truncated transgenes, which fail to produce intact mRNA, induce siRNA accumulation and silencing of...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Götz, Ulrike, Marker, Simone, Cheaib, Miriam, Andresen, Karsten, Shrestha, Simon, Durai, Dilip A., Nordström, Karl J., Schulz, Marcel H., Simon, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937312/
https://ncbi.nlm.nih.gov/pubmed/27085807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw267
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