Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease

We propose that brain energy deficit is an important pre-symptomatic feature of Alzheimer’s disease (AD) that requires closer attention in the development of AD therapeutics. Our rationale is fourfold: (i) Glucose uptake is lower in the frontal cortex of people >65 years-old despite cognitive sco...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Cunnane, Stephen C., Courchesne-Loyer, Alexandre, Vandenberghe, Camille, St-Pierre, Valérie, Fortier, Mélanie, Hennebelle, Marie, Croteau, Etienne, Bocti, Christian, Fulop, Tamas, Castellano, Christian-Alexandre
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937039/
https://ncbi.nlm.nih.gov/pubmed/27458340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00053
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