Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease

We propose that brain energy deficit is an important pre-symptomatic feature of Alzheimer’s disease (AD) that requires closer attention in the development of AD therapeutics. Our rationale is fourfold: (i) Glucose uptake is lower in the frontal cortex of people >65 years-old despite cognitive sco...

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Publicat a:Front Mol Neurosci
Autors principals: Cunnane, Stephen C., Courchesne-Loyer, Alexandre, Vandenberghe, Camille, St-Pierre, Valérie, Fortier, Mélanie, Hennebelle, Marie, Croteau, Etienne, Bocti, Christian, Fulop, Tamas, Castellano, Christian-Alexandre
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937039/
https://ncbi.nlm.nih.gov/pubmed/27458340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00053
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