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Tumor Targeting, Pharmacokinetics and Biodistribution of a Near Infrared Fluorescent-labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5

Fluorescence molecular imaging can be employed for the development of novel cancer targeting agents. Herein, we investigated the pharmacokinetics (PK), biodistribution (BD) and cellular uptake of Dmt-Tic-Cy5, a delta-opioid receptor (δOR) antagonist-fluorescent dye conjugate, as a tumor-targeting mo...

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書誌詳細
出版年:Mol Pharm
主要な著者: Huynh, Amanda Shanks, Estrella, Veronica, Stark, Valerie E., Cohen, Allison S., Chen, Tingan, Casagni, Todd J., Josan, Jatinder S., Lloyd, Mark C., Johnson, Joseph, Hruby, Victor J., Vagner, Josef, Morse, David L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936951/
https://ncbi.nlm.nih.gov/pubmed/26713599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00760
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