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Tumor Targeting, Pharmacokinetics and Biodistribution of a Near Infrared Fluorescent-labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5

Fluorescence molecular imaging can be employed for the development of novel cancer targeting agents. Herein, we investigated the pharmacokinetics (PK), biodistribution (BD) and cellular uptake of Dmt-Tic-Cy5, a delta-opioid receptor (δOR) antagonist-fluorescent dye conjugate, as a tumor-targeting mo...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Huynh, Amanda Shanks, Estrella, Veronica, Stark, Valerie E., Cohen, Allison S., Chen, Tingan, Casagni, Todd J., Josan, Jatinder S., Lloyd, Mark C., Johnson, Joseph, Hruby, Victor J., Vagner, Josef, Morse, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936951/
https://ncbi.nlm.nih.gov/pubmed/26713599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00760
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