The Type of Growth Medium Affects the Presence of a Mycobacterial Capsule and Is Associated With Differences in Protective Efficacy of BCG Vaccination Against Mycobacterium tuberculosis

Background. Bacillus Calmette-Guerin (BCG) vaccine is widely used for the prevention of tuberculosis, despite limited efficacy. Most immunological studies of BCG or Mycobacterium tuberculosis strains grow bacteria in the presence of detergent, which also strips the mycobacterial capsule. The impact...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Prados-Rosales, Rafael, Carreño, Leandro J., Weinrick, Brian, Batista-Gonzalez, Ana, Glatman-Freedman, Aarona, Xu, Jiayong, Chan, John, Jacobs, William R., Porcelli, Steven A., Casadevall, Arturo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936643/
https://ncbi.nlm.nih.gov/pubmed/27234419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw153
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