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Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction

Background. The relevance of antibodies (Abs) in the defense against Mycobacterium tuberculosis infection remains uncertain. We investigated the role of Abs to the mycobacterial capsular polysaccharide arabinomannan (AM) and its oligosaccharide (OS) fragments in humans. Methods. Sera obtained from 2...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Chen, Tingting, Blanc, Caroline, Eder, Anke Z., Prados-Rosales, Rafael, Souza, Ana Camila Oliveira, Kim, Ryung S., Glatman-Freedman, Aharona, Joe, Maju, Bai, Yu, Lowary, Todd L., Tanner, Rachel, Brennan, Michael J., Fletcher, Helen A., McShane, Helen, Casadevall, Arturo, Achkar, Jacqueline M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918826/
https://ncbi.nlm.nih.gov/pubmed/27056953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw141
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