The Type of Growth Medium Affects the Presence of a Mycobacterial Capsule and Is Associated With Differences in Protective Efficacy of BCG Vaccination Against Mycobacterium tuberculosis

Background. Bacillus Calmette-Guerin (BCG) vaccine is widely used for the prevention of tuberculosis, despite limited efficacy. Most immunological studies of BCG or Mycobacterium tuberculosis strains grow bacteria in the presence of detergent, which also strips the mycobacterial capsule. The impact...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Prados-Rosales, Rafael, Carreño, Leandro J., Weinrick, Brian, Batista-Gonzalez, Ana, Glatman-Freedman, Aarona, Xu, Jiayong, Chan, John, Jacobs, William R., Porcelli, Steven A., Casadevall, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936643/
https://ncbi.nlm.nih.gov/pubmed/27234419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw153
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