Prognostic and clinical impact of PIK3CA mutation in gastric cancer: pyrosequencing technology and literature review

BACKGROUND: Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) mutations that activate the PI3K/AKT signaling pathway have been observed in several types of carcinoma and have been associated with patient prognosis. However, the significance of PIK3CA mutations in gastr...

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Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Harada, Kazuto, Baba, Yoshifumi, Shigaki, Hironobu, Ishimoto, Takatsugu, Miyake, Keisuke, Kosumi, Keisuke, Tokunaga, Ryuma, Izumi, Daisuke, Ohuchi, Mayuko, Nakamura, Kenichi, Kiyozumi, Yuki, Kurashige, Junji, Iwatsuki, Masaaki, Miyamoto, Yuji, Sakamoto, Yasuo, Yoshida, Naoya, Watanabe, Masayuki, Baba, Hideo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936296/
https://ncbi.nlm.nih.gov/pubmed/27388016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2422-y
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