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Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis

Hepatitis C virus (HCV)-induced chronic liver disease is a leading cause of hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying HCC development following chronic HCV infection remain poorly understood. MicroRNAs (miRNAs) play an important role in homeostasis within the liver...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bandiera, Simonetta, Pernot, Sophie, El Saghire, Hussein, Durand, Sarah C., Thumann, Christine, Crouchet, Emilie, Ye, Tao, Fofana, Isabel, Oudot, Marine A., Barths, Jochen, Schuster, Catherine, Pessaux, Patrick, Heim, Markus H., Baumert, Thomas F., Zeisel, Mirjam B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936128/
https://ncbi.nlm.nih.gov/pubmed/27147737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00619-16
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