Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis

Hepatitis C virus (HCV)-induced chronic liver disease is a leading cause of hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying HCC development following chronic HCV infection remain poorly understood. MicroRNAs (miRNAs) play an important role in homeostasis within the liver...

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Bibliographic Details
Published in:J Virol
Main Authors: Bandiera, Simonetta, Pernot, Sophie, El Saghire, Hussein, Durand, Sarah C., Thumann, Christine, Crouchet, Emilie, Ye, Tao, Fofana, Isabel, Oudot, Marine A., Barths, Jochen, Schuster, Catherine, Pessaux, Patrick, Heim, Markus H., Baumert, Thomas F., Zeisel, Mirjam B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936128/
https://ncbi.nlm.nih.gov/pubmed/27147737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00619-16
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