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The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex

Forkhead-box domain (Fox) containing family members are known to play a role in neocorticogenesis and have also been associated with disorders on the autism spectrum. Here we show that a single RNA-binding protein, Hu antigen R (HuR), dictates translation specificity of bound mRNAs and is sufficient...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Popovitchenko, T., Thompson, K., Viljetic, B., Jiao, X., Kontonyiannis, D. L., Kiledjian, M., Hart, R. P., Rasin, M. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935837/
https://ncbi.nlm.nih.gov/pubmed/27383233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28998
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