7SL RNA represses p53 translation by competing with HuR

Noncoding RNAs (ncRNAs) and RNA-binding proteins are potent post-transcriptional regulators of gene expression. The ncRNA 7SL is upregulated in cancer cells, but its impact upon the phenotype of cancer cells is unknown. Here, we present evidence that 7SL forms a partial hybrid with the 3′-untranslat...

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Hlavní autoři: Abdelmohsen, Kotb, Panda, Amaresh C., Kang, Min-Ju, Guo, Rong, Kim, Jiyoung, Grammatikakis, Ioannis, Yoon, Je-Hyun, Dudekula, Dawood B., Noh, Ji Heon, Yang, Xiaoling, Martindale, Jennifer L., Gorospe, Myriam
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150789/
https://ncbi.nlm.nih.gov/pubmed/25123665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku686
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