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Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron
Diabetes increases the reabsorption of Na(+) (T(Na)) and glucose via the sodium-glucose cotransporter SGLT2 in the early proximal tubule (S1-S2 segments) of the renal cortex. SGLT2 inhibitors enhance glucose excretion and lower hyperglycemia in diabetes. We aimed to investigate how diabetes and SGLT...
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| Published in: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935777/ https://ncbi.nlm.nih.gov/pubmed/26764207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00543.2015 |
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