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SGLT2 inhibition in a kidney with reduced nephron number: modeling and analysis of solute transport and metabolism
Sodium-glucose cotransporter 2 (SGLT2) inhibitors enhance urinary glucose, Na(+) and fluid excretion, and lower hyperglycemia in diabetes by targeting Na(+) and glucose reabsorption along the proximal convoluted tubule. A goal of this study was to predict the effects of SGLT2 inhibitors in diabetic...
Tallennettuna:
| Julkaisussa: | Am J Physiol Renal Physiol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031905/ https://ncbi.nlm.nih.gov/pubmed/29361669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00551.2017 |
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