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SGLT2 inhibition in a kidney with reduced nephron number: modeling and analysis of solute transport and metabolism

Sodium-glucose cotransporter 2 (SGLT2) inhibitors enhance urinary glucose, Na(+) and fluid excretion, and lower hyperglycemia in diabetes by targeting Na(+) and glucose reabsorption along the proximal convoluted tubule. A goal of this study was to predict the effects of SGLT2 inhibitors in diabetic...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Renal Physiol
Asıl Yazarlar: Layton, Anita T., Vallon, Volker
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031905/
https://ncbi.nlm.nih.gov/pubmed/29361669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00551.2017
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