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Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition

The objective of this study was to investigate how physiological, pharmacological, and pathological conditions that alter sodium reabsorption (T(Na)) in the proximal tubule affect oxygen consumption (Q(O(2))) and Na(+) transport efficiency (T(Na)/Q(O(2))). To do so, we expanded a mathematical model...

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Detalles Bibliográficos
Publicado en:Am J Physiol Renal Physiol
Autores principales: Layton, Anita T., Vallon, Volker, Edwards, Aurélie
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469883/
https://ncbi.nlm.nih.gov/pubmed/25855513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00007.2015
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