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Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition

The objective of this study was to investigate how physiological, pharmacological, and pathological conditions that alter sodium reabsorption (T(Na)) in the proximal tubule affect oxygen consumption (Q(O(2))) and Na(+) transport efficiency (T(Na)/Q(O(2))). To do so, we expanded a mathematical model...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Layton, Anita T., Vallon, Volker, Edwards, Aurélie
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469883/
https://ncbi.nlm.nih.gov/pubmed/25855513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00007.2015
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