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Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition

The objective of this study was to investigate how physiological, pharmacological, and pathological conditions that alter sodium reabsorption (T(Na)) in the proximal tubule affect oxygen consumption (Q(O(2))) and Na(+) transport efficiency (T(Na)/Q(O(2))). To do so, we expanded a mathematical model...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Renal Physiol
Huvudupphovsmän: Layton, Anita T., Vallon, Volker, Edwards, Aurélie
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469883/
https://ncbi.nlm.nih.gov/pubmed/25855513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00007.2015
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