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The CUL3/KLHL3-WNK-SPAK/OSR1 pathway as a target for antihypertensive therapy

Chronic high blood pressure (hypertension) is the most common disease in the Unites States. While several classes of drugs exist to treat it, many patients (up to 10 million Americans) respond poorly to therapy, even when multiple classes are used. Recent evidence suggests that a significant portion...

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Bibliographic Details
Published in:Am J Physiol Renal Physiol
Main Authors: Ferdaus, Mohammed Z., McCormick, James A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935775/
https://ncbi.nlm.nih.gov/pubmed/27076645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00132.2016
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