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The CUL3/KLHL3-WNK-SPAK/OSR1 pathway as a target for antihypertensive therapy

Chronic high blood pressure (hypertension) is the most common disease in the Unites States. While several classes of drugs exist to treat it, many patients (up to 10 million Americans) respond poorly to therapy, even when multiple classes are used. Recent evidence suggests that a significant portion...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Ferdaus, Mohammed Z., McCormick, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935775/
https://ncbi.nlm.nih.gov/pubmed/27076645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00132.2016
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