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Identification of the WNK-SPAK/OSR1 Signaling Pathway in Rodent and Human Lenses

PURPOSE. To identify whether the kinases that regulate the activity of cation chloride cotransporters (CCC) in other tissues are also expressed in rat and human lenses. METHODS. The expression of with-no-lysine kinase (WNK 1, 3, 4), oxidative stress response kinase 1 (OSR1), and Ste20-like proline a...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Vorontsova, Irene, Lam, Leo, Delpire, Eric, Lim, Julie, Donaldson, Paul
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294287/
https://ncbi.nlm.nih.gov/pubmed/25515571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15911
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