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WNK-SPAK/OSR1-NCC kinase signaling pathway as a novel target for the treatment of salt-sensitive hypertension

Hypertension is the most prevalent health condition worldwide, affecting ~1 billion people. Gordon’s syndrome is a form of secondary hypertension that can arise due to a number of possible mutations in key genes that encode proteins in a pathway containing the With No Lysine [K] (WNK) and its downst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Brown, Archie, Meor Azlan, Nur Farah, Wu, Zhijuan, Zhang, Jinwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115323/
https://ncbi.nlm.nih.gov/pubmed/32724175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0474-7
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