Llwytho...
Total Synthesis of (+)-SCH 351448: Efficiency via Chemoselectivity and Redox-Economy Powered by Metal Catalysis
The polyketide natural product (+)-SCH 351448, a macrodiolide ionophore bearing 14 stereogenic centers, is prepared in 14 steps (LLS). In 8 prior syntheses, 22–32 steps were required. Multiple chemoselective and redox-economic functional group interconversions collectively contribute to a step-chang...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Am Chem Soc |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935581/ https://ncbi.nlm.nih.gov/pubmed/27337561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b04917 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|