Two ways to skin a cat: ADEP antibiotics can kill bacteria through activation or inhibition of ClpP activity

Benzer Materyaller

• The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease
  Yazar:: Kirstein, Janine, ve diğerleri
  Baskı/Yayın Bilgisi: (2009)
• Ureadepsipeptides as ClpP Activators
  Yazar:: Griffith, Elizabeth C., ve diğerleri
  Baskı/Yayın Bilgisi: (2019)
• The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory clpP Gene as a Novel Antibiotic Resistance Factor
  Yazar:: Thomy, Dhana, ve diğerleri
  Baskı/Yayın Bilgisi: (2019)
• Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease
  Yazar:: Famulla, Kirsten, ve diğerleri
  Baskı/Yayın Bilgisi: (2016)
• Killing persister cells and eradicating a biofilm infection by activating the ClpP protease
  Yazar:: Conlon, BP, ve diğerleri
  Baskı/Yayın Bilgisi: (2013)