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p38 MAPK α and β isoforms differentially regulate plasma membrane localization of MRP2
In hepatocytes, cAMP both activates p38 mitogen-activated protein kinase (MAPK) and increases the amount of multidrug resistance-associated protein-2 (MRP2) in the plasma membrane (PM-MRP2). Paradoxically, taurolithocholate (TLC) activates p38 MAPK but decreases PM-MRP2 in hepatocytes. These opposin...
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| Publicado en: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935486/ https://ncbi.nlm.nih.gov/pubmed/27012769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00005.2016 |
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