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Protection of HepG2 cells against acrolein toxicity by 2-cyano-3,12-dioxooleana-1,9-dien-28-imidazolide via glutathione-mediated mechanism

Acrolein is an environmental toxicant, mainly found in smoke released from incomplete combustion of organic matter. Several studies showed that exposure to acrolein can lead to liver damage. The mechanisms involved in acrolein-induced hepatocellular toxicity, however, are not completely understood....

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Bibliografische gegevens
Gepubliceerd in:Exp Biol Med (Maywood)
Hoofdauteurs: Shah, Halley, Speen, Adam M, Saunders, Christina, Brooke, Elizabeth AS, Nallasamy, Palanisamy, Zhu, Hong, Li, Y Robert, Jia, Zhenquan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935256/
https://ncbi.nlm.nih.gov/pubmed/25504014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214563900
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