Protection of HepG2 cells against acrolein toxicity by 2-cyano-3,12-dioxooleana-1,9-dien-28-imidazolide via glutathione-mediated mechanism

Acrolein is an environmental toxicant, mainly found in smoke released from incomplete combustion of organic matter. Several studies showed that exposure to acrolein can lead to liver damage. The mechanisms involved in acrolein-induced hepatocellular toxicity, however, are not completely understood....

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Shah, Halley, Speen, Adam M, Saunders, Christina, Brooke, Elizabeth AS, Nallasamy, Palanisamy, Zhu, Hong, Li, Y Robert, Jia, Zhenquan
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935256/
https://ncbi.nlm.nih.gov/pubmed/25504014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214563900
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