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WWOX, the chromosomal fragile site FRA16D spanning gene: Its role in metabolism and contribution to cancer

The WWOX gene spans the common chromosomal fragile site FRA16D that is located within a massive (780 kb) intron. The WWOX gene is very long, at 1.1 Mb, which may contribute to the very low abundance of the full-length 1.4 kb mRNA. Alternative splicing also accounts for a variety of aberrant transcri...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Richards, Robert I, Choo, Amanda, Lee, Cheng Shoou, Dayan, Sonia, O’Keefe, Louise
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935231/
https://ncbi.nlm.nih.gov/pubmed/25595186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214565990
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