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Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogaster

WWOX is a >1Mb gene spanning FRA16D Common Chromosomal Fragile Site, a region of DNA instability in cancer. Consequently, altered WWOX levels have been observed in a wide variety of cancers. In vitro studies have identified a large number and variety of potential roles for WWOX. Although its norm...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: O’Keefe, Louise V., Lee, Cheng Shoou, Choo, Amanda, Richards, Robert I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547717/
https://ncbi.nlm.nih.gov/pubmed/26302329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136356
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