Involvement of a proapoptotic gene (BBC3) in islet injury mediated by cold preservation and rewarming

Long-term pancreatic cold ischemia contributes to decreased islet number and viability after isolation and culture, leading to poor islet transplantation outcome in patients with type 1 diabetes. In this study, we examined mechanisms of pancreatic cold preservation and rewarming-induced injury by in...

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Publié dans:Am J Physiol Endocrinol Metab
Auteurs principaux: Omori, Keiko, Kobayashi, Eiji, Komatsu, Hirotake, Rawson, Jeffrey, Agrawal, Garima, Parimi, Mounika, Oancea, Alina R., Valiente, Luis, Ferreri, Kevin, Al-Abdullah, Ismail H., Kandeel, Fouad, Takahashi, Masafumi, Mullen, Yoko
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935146/
https://ncbi.nlm.nih.gov/pubmed/27117005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00441.2015
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