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Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival.

Type 1 diabetes is an autoimmune disease that destroys insulin-producing beta cells in the pancreas. Pancreatic islet transplantation could be an effective treatment option for type 1 diabetes once several issues are resolved, including donor shortage, prevention of islet necrosis and loss in pre- a...

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Autors principals: Hirotake Komatsu, Colin Cook, Chia-Hao Wang, Leonard Medrano, Henry Lin, Fouad Kandeel, Yu-Chong Tai, Yoko Mullen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2017-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC5568442?pdf=render
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