Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival

BACKGROUND: Type 1 diabetes is an autoimmune disease that destroys insulin-producing beta cells in the pancreas. Pancreatic islet transplantation could be an effective treatment option for type 1 diabetes once several issues are resolved, including donor shortage, prevention of islet necrosis and lo...

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Udgivet i:PLoS One
Main Authors: Komatsu, Hirotake, Cook, Colin, Wang, Chia-Hao, Medrano, Leonard, Lin, Henry, Kandeel, Fouad, Tai, Yu-Chong, Mullen, Yoko
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568442/
https://ncbi.nlm.nih.gov/pubmed/28832685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183780
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